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Current Issue - November 2009, Volume 3, Issue No. 2

Official Journal of Malaysian Orthopaedic Association

Intrarticular Sodium Hyaluronate for the Treatment of Osteoarthritis of the Knee. A Retrospective Review of 45 Patients


  1. Snibbe JC, Gambardella, RA. Treatment options for osteoarthritis. Orthopedics, 2005; 28(2 Suppl): 215-20.
  2. Aggarwal A, Sempowski, IP. Hyaluronic acid injections for knee osteoarthritis. Systematic review of the literature. Can Fam Physician, 2004; 50: 249-56.
  3. Guidolin DD, Ronchetti IP, Lini E, Guerra D, Frizziero L. Morphological analysis of articular cartilage biopsies from a randomized, clinical study comparing the effects of 500-730 kDa sodium hyaluronate (Hyalgan) and methylprednisolone acetate on primary osteoarthritis of the knee. Osteoarthritis Cartilage, 2001; 9(4): 371-81.
  4. Meloni F, Milia F, Cavazzuti M, Doria C, Lisai P, Profili S, et al, Clinical evaluation of sodium hyaluronate in the treatment of patients with sopraspinatus tendinosis under echographic guide: Experimental study of periarticular injections. Eur J Radiol, 2008; 68(1): 170-3.
  5. Turajane T, Labpiboonpong V, Maungsiri S. Cost analysis of intra-articular sodium hyaluronate treatment in knee osteoarthritis patients who failed conservative treatment. J Med Assoc Thai, 2007; 90(9): 1839-44.
  6. Adams ME, Lussier AJ, Peyron JG. A risk-benefit assessment of injections of hyaluronan and its derivatives in the treatment of osteoarthritis of the knee. Drug Saf, 2000; 23(2): 115-30.
  7. Uthman I, Raynauld JP, Haraoui B. Intra-articular therapy in osteoarthritis. Postgrad Med J, 2003; 79(934): 449-53.
  8. Jubb RW, Piva S, Beinat L, Dacre J, Gishen P. A one-year, randomised, placebo (saline) controlled clinical trial of 500-730 kDa sodium hyaluronate (Hyalgan) on the radiological change in osteoarthritis of the knee. Int J Clin Pract, 2003; 57(6): 467-74.
  9. Toh EM, Prasad PS, Teanby D. Correlating the efficacy of knee viscosupplementation with osteoarthritic changes on roentgenological examination. Knee, 2002; 9(4): 321-30.
  10. Roman JA, Chismol J, Morales M, Donderis JL. Intra-articular treatment with hyaluronic acid. Comparative study of Hyalgan and Adant. Clin Rheumatol, 2000; 19(3): 204-6.
  11. Kotz R, Kolarz G. Intra-articular hyaluronic acid: Duration of effect and results of repeated treatment cycles. Am J Orthop, 1999; 28(11 Suppl): 5-7.
  12. Bunyaratavej N, Chan KM, Subramanian N. Treatment of painful osteoarthritis of the knee with hyaluronic acid. Results of a multicenter Asian study. J Med Assoc Thai, 2001; 84 Suppl 2: 576-81.
  13. Huskisson EC, Donnelly S. Hyaluronic acid in the treatment of osteoarthritis of the knee. Rheumatology (Oxford), 1999; 38(7):602-7.
  14. Frizziero L, Govoni E, Bacchini P. Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: Clinical and morphological study. Clin Exp Rheumatol, 1998; 16(4): 441-9.
  15. Turajane T, Tanavaree A, Labpiboonpong V, Maungsiri S. Outcomes of intra-articular injection of sodium hyaluronate for the treatment of osteoarthritis of the knee. J Med Assoc Thai, 2007; 90(9): 1845-52.

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About Us

The Malaysian Orthopaedic Journal is a peer-reviewed journal that is published three times a year in both print and electronic online version. The purpose of this journal is to publish original research studies, evaluation of current practices and case reports in various subspecialties of orthopaedics and traumatology, as well as associated fields like basic science, biomedical engineering, rehabilitation medicine and nursing.

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