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Current Issue - November 2009, Volume 3, Issue No. 2

Official Journal of Malaysian Orthopaedic Association

Simvastatin Induced Rhabdomyolysis of Anterior Compartment of Leg Resulting in Foot Drop

Abstract

A 65-year-old physically active man presented with sudden onset leg pain and inability to dorsiflex his foot following a trivial fall. There was no tenseness in the anterior compartment and compartment pressure was normal. Three days later he developed erythema with pitting oedema of the leg. Serum creatine kinase was 14000 U/l initially which gradually decreased. Subsequent Doppler scans and MRI showed evidence of myositis involving the entire anterior compartment. The patient reported a history of simvastatin use for the past year. A nerve conduction study confirmed common peroneal nerve palsy. This case report highlights a rare complication of simvastatin use presenting with foot drop resulting from muscle damage and nerve palsy.

Abstract   |   Reference

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The Malaysian Orthopaedic Journal is a peer-reviewed journal that is published three times a year in both print and electronic online version. The purpose of this journal is to publish original research studies, evaluation of current practices and case reports in various subspecialties of orthopaedics and traumatology, as well as associated fields like basic science, biomedical engineering, rehabilitation medicine and nursing.

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