Importance of Appropriate and Substantial Imaging and Pathological Information for Rare Conditions
Abstract
We read with interest the paper by Indra et al titled “Pigmented Villonodular Synovitis (PVNS) of the Knee mimicking Septic Arthritis in a Paediatric Patient: A Case Report”. We would like to thank the authors for publishing this interesting case. Our comment highlights the imaging and pathological findings that are required to better understand the nature of this case. It has been reported that PVNS (currently unified in tenosynovial giant cell tumour) is sometimes difficult to distinguish from juvenile idiopathic arthritis, haemophilic arthropathy, and other malignant disorders in paediatric cases. Magnetic resonance imaging (MRI) plays a pivotal role in differential diagnosis. Determining the extent of inflammation and the presence or absence of tumours on a single MRI image is extremely challenging. If other cross-sectional information were available, such as FS or STIR on T2WI or contrast-enhanced T1WI, it would be easier for the reader to determine the extent of inflammation (not only intra-articular but also bone marrow) and differentiate it from tumours. T2*-WI is also useful for detecting hemosiderin.
Abstract | Reference
