MOJ Header

Current Issue - March 2023, Volume 17, Issue No. 1

Official Journal of Malaysian Orthopaedic Association and ASEAN Orthopaedic Association

Is Follow-up Co-Morbidity Assessment via Laboratory Investigations in Older High Energy Trauma Patients Justified? - A Prospective-Retrospective Study


  1. Lowe JA, Pearson J, Leslie M, Griffin R. Ten-Year Incidence of High-Energy Geriatric Trauma at a Level 1 Trauma Center. J Orthop Trauma. 2018; 32(3): 129-33. doi: 10.1097/BOT.0000000000001052
  2. Rzepka SG, Malangoni MA, Rimm AA. Geriatric trauma hospitalization in the United States: a population-based study. J Clin Epidemiol. 2001; 54(6): 627-33. doi: 10.1016/s0895-4356(00)00337-1
  3. Bonne S, Schuerer DJ. Trauma in the older adult: epidemiology and evolving geriatric trauma principles. Clin Geriatr Med. 2013; 29(1): 137-50. doi: 10.1016/j.cger.2012.10.008
  4. Compston J, Cooper A, Cooper C, Gittoes N, Gregson C, Harvey N, et al. UK clinical guideline for the prevention and treatment of osteoporosis. Arch Osteoporos. 2017; 12(1): 43. doi: 10.1007/s11657-017-0324-5
  5. Bours SP, van Geel TA, Geusens PP, Janssen MJ, Janzing HM, Hoffland GA, et al. Contributors to secondary osteoporosis and metabolic bone diseases in patients presenting with a clinical fracture. J Clin Endocrinol Metab. 2011; 96(5): 1360-7. doi: 10.1210/jc.2010-2135
  6. Watts NB, Bilezikian JP, Camacho PM, Greenspan SL, Harris ST, Hodgson SF, et al. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis: executive summary of recommendations. Endocr Pract. 2010; 16(6): 1016-9. doi: 10.4158/ep.16.6.1016
  7. Chan DD, Chang LY, Akesson KE, Mitchell P, Chen CH, Lewiecki EM, et al. Consensus on best practice standards for Fracture Liaison Service in the Asia-Pacific region. Arch Osteoporos. 2018; 13(1): 59. doi: 10.1007/s11657-018-0463-3
  8. Lorenc R, Gluszko P, Franek E, Jablonski M, Jaworski M, Kalinka, et al. Guidelines for the diagnosis and management of osteoporosis in Poland : Update 2017. Endokrynol Pol. 2017; 68(5): 604-9. doi: 10.5603/EP.2017.0062
  9. Neuerburg C, Mittlmeier L, Schmidmaier R, Kammerlander C, Bocker W, Mutschler W, et al. Investigation and management of osteoporosis in aged trauma patients: a treatment algorithm adapted to the German guidelines for osteoporosis. J Orthop Surg Res. 2017; 12(1): 86. doi: 10.1186/s13018-017-0585-0
  10. Inderjeeth CA, Raymond WD, Briggs AM, Geelhoed E, Oldham D, Mountain D. Implementation of the Western Australian Osteoporosis Model of Care: a fracture liaison service utilising emergency department information systems to identify patients with fragility fracture to improve current practice and reduce re-fracture rates: a 12-month analysis. Osteoporos Int. 2018; 29(8): 1759-70. doi: 10.1007/s00198-018-4526-5
  11. Binkley N, Coursin D, Krueger D, Iglar P, Heiner J, Illgen R, et al. Surgery alters parameters of vitamin D status and other laboratory results. Osteoporos Int. 2017; 28(3): 1013-20. doi: 10.1007/s00198-016-3819-9
  12. Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009; 150(9): 604-12. doi: 10.7326/0003-4819-150-9-200905050-00006
  13. Kaji H, Yamauchi M, Yamaguchi T, Shigematsu T, Sugimoto T. Mild renal dysfunction is a risk factor for a decrease in bone mineral density and vertebral fractures in Japanese postmenopausal women. J Clin Endocrinol Metab. 2010; 95(10): 4635-42. doi: 10.1210/jc.2010-0099
  14. Kanis JA. Diagnosis of osteoporosis and assessment of fracture risk. Lancet. 2002; 359(9321): 1929-36. doi: 10.1016/S0140-6736(02)08761-5
  15. Cummings SR, Bates D, Black DM. Clinical use of bone densitometry: scientific review. JAMA. 2002; 288(15): 1889-97. doi: 10.1001/jama.288.15.1889
  16. Makker A, Mishra G, Singh BP, Tripathi A, Singh MM. Normative bone mineral density data at multiple skeletal sites in Indian subjects. Arch Osteoporos. 2008; 3(1): 25-37. doi: 10.1007/s11657-008-0019-z
  17. de Klerk G, Hegeman JH, van der Velde D, van der Palen J, van Bergeijk L, Duis HJ. The value of laboratory tests in diagnosing secondary osteoporosis at a fracture and osteoporosis outpatient clinic. Geriatr Orthop Surg Rehabil. 2013; 4(2): 53-7. doi: 10.1177/2151458513501176
  18. Jamal SA, Leiter RE, Bayoumi AM, Bauer DC, Cummings SR. Clinical utility of laboratory testing in women with osteoporosis. Osteoporos Int. 2005; 16(5): 534-40. doi: 10.1007/s00198-004-1718-y
  19. Malgo F, Appelman-Dijkstra NM, Termaat MF, van der Heide HJ, Schipper IB, Rabelink TJ, et al. High prevalence of secondary factors for bone fragility in patients with a recent fracture independently of BMD. Arch Osteoporos. 2016; 11(1): 12. doi: 10.1007/s11657-016-0258-3
  20. Siris ES, Miller PD, Barrett-Connor E, Faulkner KG, Wehren LE, Abbott TA, et al. Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment. JAMA. 2001; 286(22): 2815-22. doi: 10.1001/jama.286.22.2815
  21. Diamantopoulos AP, Rohde G, Johnsrud I, Skoie IM, Hochberg M, Haugeberg G. The epidemiology of low- and high-energy distal radius fracture in middle-aged and elderly men and women in Southern Norway. PLoS One. 2012; 7(8): e43367. doi: 10.1371/journal.pone.0043367
  22. He QF, Sun H, Shu LY, Zhan Y, He CY, Zhu Y, et al. Tibial plateau fractures in elderly people: an institutional retrospective study. J Orthop Surg Res. 2018; 13(1): 276. doi: 10.1186/s13018-018-0986-8
  23. Hahnhaussen J, Hak DJ, Weckbach S, Ertel W, Stahel PF. High-energy proximal femur fractures in geriatric patients: a retrospective analysis of short-term complications and in-hospital mortality in 32 consecutive patients. Geriatr Orthop Surg Rehabil. 2011; 2(5-6): 195-202. doi: 10.1177/2151458511427702
  24. Mavilia MG, Bhardwaj R, Wakefield D, Karagozian R. Chronic Liver Disease Patients have Worse Outcomes and Increased Postoperative Complications After Orthopedic Fractures. J Clin Gastroenterol. 2019; 53(9): e371-5. doi: 10.1097/MCG.0000000000001166
  25. Fisher L, Srikusalanukul W, Fisher A, Smith P. Liver function parameters in hip fracture patients: relations to age, adipokines, comorbidities and outcomes. Int J Med Sci. 2015; 12(2): 100-15. doi: 10.7150/ijms.10696
  26. Do HJ, Shin JS, Lee J, Lee YJ, Kim MR, Nam D, et al. Association between liver enzymes and bone mineral density in Koreans: a cross-sectional study. BMC Musculoskelet Disord. 2018; 19(1): 410. doi: 10.1186/s12891-018-2322-1
  27. Robertson L, Black C, Fluck N, Gordon S, Hollick R, Nguyen H, et al. Hip fracture incidence and mortality in chronic kidney disease: the GLOMMS-II record linkage cohort study. BMJ Open. 2018; 8(4): e020312. doi: 10.1136/bmjopen-2017-020312
  28. Geng S, Kuang Z, Peissig PL, Page D, Maursetter L, Hansen KE. Parathyroid hormone independently predicts fracture, vascular events, and death in patients with stage 3 and 4 chronic kidney disease. Osteoporos Int. 2019; 30(10): 2019-25. doi: 10.1007/s00198-019-05033-3
  29. Lewiecki EM, Miller PD. Skeletal effects of primary hyperparathyroidism: bone mineral density and fracture risk. J Clin Densitom. 2013; 16(1): 28-32. doi: 10.1016/j.jocd.2012.11.013
  30. Lee JS, Kim JW. Prevalence of vitamin D deficiency in postmenopausal high- and low-energy fracture patient. Arch Osteoporos. 2018; 13(1): 109. doi: 10.1007/s11657-018-0524-7
  31. Suryanarayana P, Arlappa N, Sai Santhosh V, Balakrishna N, Lakshmi Rajkumar P, Prasad U, et al. Prevalence of vitamin D deficiency and its associated factors among the urban elderly population in Hyderabad metropolitan city, South India. Ann Hum Biol. 2018; 45(2): 133-9. doi: 10.1080/03014460.2018.1425479
  32. Court-Brown CM, Heckman JD, McQueen MM, Ricci WM, Tornetta P, McKee MD, editors. Rockwood and Green's fractures in adults. 8th ed. Philadelphia: Wolters Kluwer Health; 2015. 2077 p.
  33. Zhao JG, Zeng XT, Wang J, Liu L. Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis. JAMA. 2017; 318(24): 2466-82. doi: 10.1001/jama.2017.19344
  34. Kwak MK, Choi D, Lee JH, Kim HJ, Park HK, Suh KI, et al. Relationship between Decrease in Serum Sodium Level and Bone Mineral Density in Osteoporotic Fracture Patients. J Bone Metab. 2015; 22(1): 9-15. doi: 10.11005/jbm.2015.22.1.9
  35. Negri AL, Ayus JC. Hyponatremia and bone disease. Rev Endocr Metab Disord. 2017; 18(1): 67-78. doi: 10.1007/s11154-016-9387-7
  36. Sheehan KJ, Williamson L, Alexander J, Filliter C, Sobolev B, Guy P, et al. Prognostic factors of functional outcome after hip fracture surgery: a systematic review. Age Ageing. 2018; 47(5): 661-70. doi: 10.1093/ageing/afy057

Abstract   |   Reference

MOJ footer

About Us

The Malaysian Orthopaedic Journal is a peer-reviewed journal that is published three times a year in both print and electronic online version. The purpose of this journal is to publish original research studies, evaluation of current practices and case reports in various subspecialties of orthopaedics and traumatology, as well as associated fields like basic science, biomedical engineering, rehabilitation medicine and nursing.

Keep in Touch

creative-commons License